3.5 Genetic modification and biotechnology

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3.5 Genetic modification and biotechnology

3.5 Genetic modification and biotechnology

Concept mapping of the 3.5 Genetic modification + Biotechnology

Knowledge control of 3.5 Genetic modification + Biotechnology

Essential idea:

3.5.1  Biologists have developed techniques for artificial manipulation of DNA, cells and organisms.

Recombinant DNA technology video

 

How Restriction endonucleases works? Animation

 

Restriction Fragment Length Polymorphisms (RFA)  

 

Nature of science:

 

3.5.2  Assessing risks associated with scientific research—scientists attempt to assess the risks associated with genetically modified crops or livestock. (4.8)

 

Understandings:

 

 

3.5.3  Gel electrophoresis is used to separate proteins or fragments of DNA

according to size.

 

Gel electrophoresis animation

 

Gel Electrophoresis

Electrophoresis activity 

 

3.5.4  PCR can be used to amplify small amounts of DNA.

 

The Polymerase Chain Reaction interactive animation

 

http://learn.genetics.utah.edu/content/labs/pcr/ PCR virtual lab

 

The Polymerase Chain Reaction animation

 

The PCR song

 

The PCR song with animation

 

3.5.5  DNA profiling involves comparison of DNA.

 

DNA Microarray

 

Experiments & Techniques: Microarray

 

3.5.6  Genetic modification is carried out by gene transfer between species.

 

Article-Taiwan breeds green-glowing pigs

 

Glowing Pig Passes Genes to Piglets

 

Article,Crusaders Against GMOs

 

IB Genetic Engineering & Biotechnology video

 

GMO Compass

 

Search the register for products containing GMOs

 

Genes or Organisms

 

GM Crop Database

 

Genetically modified organisms and Invasive species in Europe.

 

3.5.7  Clones are groups of genetically identical organisms, derived from a single original parent cell.

 

Cloning ınteractive animation

 

3.5.8  Many plant species and some animal species have natural methods of

cloning.

 

 

3.5.9  Animals can be cloned at the embryo stage by breaking up the embryo into more than one group of cells.

 

Steps in cloning

 

 

3.5.10  Methods have been developed for cloning adult animals using differentiated cells.

 

 

Applications:

 

 

3.5.11  Application: Use of DNA profiling in paternity and forensic investigations.

 

3.5.12  Application: Gene transfer to bacteria using plasmids makes use of restriction endonucleases and DNA ligase.

 

3.5.13  Application: Assessment of the potential risks and benefits associated with genetic modification of crops.

 

3.5.14  Application: Production of cloned embryos produced by somatic-cell nuclear

transfer.

 

Skills:

 

3.5.15  Skill: Design of an experiment to assess one factor affecting the rooting of stem-cuttings.

 

3.5.16  Skill: Analysis of examples of DNA profiles.

 

3.5.17  Skill: Analysis of data on risks to monarch butterflies of Bt crops.

 

 

Guidance:

 

3.5.18  Students should be able to deduce whether or not a man could be the father of a child from the pattern of bands on a DNA profile.

 

 

3.5.19  Dolly can be used as an example of somatic-cell transfer.

 

 

3.5.20  A plant species should be chosen for rooting experiments that forms roots readily in water or a solid medium.

 

 

Theory of knowledge:

 

 

3.5.21  The use of DNA for securing convictions in legal cases is well established,yet even universally accepted theories are overturned in the light of new evidence in science. What criteria are necessary for assessing the reliability of evidence?

 

A variety of genetic resources

 

Utilization:

 

3.5.22  Syllabus and cross-curricular links:

Biology

Topic 2.7 DNA replication, transcription and translation

 

 

Aims:

 

3.5.23  Aim 6: The design of a rooting experiment should ideally lead to the

experiment actually being carried out by students.

               

               Aim 8: The ethics of genetic modification could be discussed.

 

Gene therapy success 'reverses' blindness

 

Severed combined immunodefiency

3.5 Genetic modification + Biotechnology Presentation 

3.5 Genetic modification + Biotechnology Animations/Videos

3.5 Genetic modification + Biotechnology  Past Paper Questions

3.5 Genetic modification + Biotechnology  Articles




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