3.1 Genes

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3.1 Genes

Topic 3: Genetics                                                                                                                                                                                         15 Hours   

3.1 Genes

Concept mapping of the 3.1 Genes

Knowledge control of  3.1 Genes 

 

Essential idea:

 

3.1.1  Every living organism inherits a blueprint for life from its parents.

 

Great videos about genetics

 

Genetic science learning center

 

Several genetic videos

 

Educator resources

 

Tour of Basic Genetics

 

Teach.Genetics

 

DNA, CHROMOSOME  FLASH

 

Nature of science:

 

3.1.2  Developments in scientific research follow improvements in technology—gene sequencers are used for the sequencing of genes. (1.8)

 

An interactive timeline of milestones in genetics

 

Understandings:

 

3.1.3  A gene is a heritable factor that consists of a length of DNA and influences a specific characteristic.

 

Great resources about Genetics “DNA from the beginning”

 

3.1.4  A gene occupies a specific position on a chromosome.

 

What is a gene?

 

What are genes?

 

3.1.5  The various specific forms of a gene are alleles.

 

What is chromosome?

 

DNA coiling animation

 

3.1.6  Alleles differ from each other by one or only a few bases.

 

 

3.1.7  New alleles are formed by mutation.

 

Changes in chromosome structure

 

3.1.8  The genome is the whole of the genetic information of an organism.

 

 

3.1.9  The entire base sequence of human genes was sequenced in the Human Genome Project

 

Applications:

 

3.1.10  Application: The causes of sickle cell anemia, including a base substitution mutation, a change to the base sequence of mRNA transcribed from it and a change to the sequence of a polypeptide in hemoglobin.

 

Normal/Abnormal hemoglobin 

 

Structure of  hemoglobin

  

Hemoglobin and sickle cell anemia video

 

Mutations and base substitution

 

What Is Sickle Cell Anemia?

 

Sickle Cell Anemia Video?

 

3.1.11  Application: Comparison of the number of genes in humans with other species.

 

Gene Screen/ iTunes/Apps

 

 

Skills:

 

3.1.12  Skill: Use of a database to determine differences in the base sequence of a gene in two species.

 

 

Guidance:

 

3.1.13  Students should be able to recall one specific base substitution that causes glutamic acid to be substituted by valine as the sixth amino acid in the hemoglobin polypeptide.

 

3.1.14   The number of genes in a species should not be referred to as genome size as this term is used for the total amount of DNA. At least one plant and one bacterium should be included in the comparison and at least one species with more genes and one with fewer genes than a human.

 

 

3.1.15  The Genbank® database can be used to search for DNA base sequences. The cytochrome C gene sequence is available for many different organisms and is of particular interest because of its use in reclassifying organisms into three domains.

 

3.1.16   Deletions, insertions and frame shift mutations do not need to be included.

 

 

International-mindedness:

 

 

3.1.17  Sequencing of the human genome shows that all humans share the vast majority of their base sequences but also that there are many single nucleotide polymorphisms that contribute to human diversity.

 

 

Theory of knowledge:

 

3.1.18  There is a link between sickle cell anemia and prevalence of malaria. How can we know whether there is a causal link in such cases or simply a correlation?

 

 

Aims:

 

3.1.19  Aim 7: The use of a database to compare DNA base sequences.

• Aim 8: Ethics of patenting human genes.

 

Gender Testing of Athletes

Addition and deletion mutations

Mutation animations

3.1 Genes Animations/ Videos

3.1 Articles

TOPIC 3 PAST PAPER QUESTIONS

Genetıc Terms

TOPIC 3 SOURCES,RELATED WITH NEW  # IBBIO SYLLABUS




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